Phoebe,wants to move on with her own life;she signs a lease for a new apartment,and Paige considers moving in with Henry.However a demon shrinks the sisters and traps them in a replica dollhouse of the Manor.
Wen a demon escapes from custody, Agent Murphy enlists the Charmed Ones help, where they learn a government created a virus spreading amongst magical beings,Meanwhile Billie becomes infected with the virus & it's up 2 the sisters 2 find an antidote.