Harley would be cool, but I really don't see it happening without The Joker.

or maybe Amanda Peet :)

nosemuffin has a good point tho. Dammit Harley's always been a fav of mine 2

Yeah I agree nosemuffin. Didn't they cast someone as Harley Quinn for The Dark Knight though? I remember seeing it on IMDB and getting excited but then I heard that she had been cut out of it.

i think all these ppl r 2 old
harley quinn is like right out of college

Nope, the backstory for Harley puts her older. Isn't she a doctor in Arkham that falls for Joker while treating him? So she woulodn't be that young.

I love Harley. I want her in Batman 3!

yes, she is a doctor, but anyway, how can u people vote for scarlett? she is extreimly gorgeus but i dont see her like a lunatic. I consider that Britany Murphy will be better firts in the aparience, and so she is a great actress. And Cristina Ricci could be a great selection too. She has this big dark halo thing.

I love Harley, however... with out the Joker, I dont see her making an appearance. Harley has to have Mr. J, he's the whole reason why she goes insane and becomes Harley Quinn! She treats the Joker, and she falls madly in love with him... How is that possible if there is no more Joker? However if Heath didn't pass on, I totally could see Harley Quinn and the Joker appearing in a new Batman film. Harley kind of has a sweet/crazy thing going on. So who knows. Plus she was casted in The Dark Knight. They had a scene that showed at the end of the credits where it introduced her but they cut it out because Heath passed away and the JOker wasn't going to be shown anymore.

Here's how i think they could add her into the 3rd movie. She is a Psychiatrist working at arkham who has had an obsession with the joker ever since he appeared. now after he is 'gone' she realises she has deep feelings for him, so starts where he left off. Also i think this movie should use more of Arkham. With Anthony Hopkins as Hugo Strange, Kathryn Morris as Harley Quinn.

Ok first SHERI MOON ZOMBIE was born to play Harley Quinn. She has that "Baby" voice and she pulls off the baby voice badgering thing PERFECTLY! I think Sheri would really make her mark and do what Jack Nicholson did for the Joker. She also has the most experience playing a love crazed murderer. Sheri Moon Zombie is Perfect for the role. I would to see it happen. Megan Fox for CATWOMAN!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!­!!!­!!!­!!!­!!!­!!!­!!!­!

I think that it would be hard to top Rachel McAdams.
She is young but not too young, she's very energetic, and she looks closer to Harley than anyone I've seen. She's a better actress than any of the people above, and she could pull of the doctor part too.
There are a few pictures proving my point here:
link
about 2/3 down the page.

i would pick Brittany Murphy but she's dead so yeah.

sarah will be allsome if she plays harley quinn.

I'd loved to see her in the role but she's dead so now i don't know :s

I'm so very sorry to say that Britanny Murphy has passed away from a drug overdose!!!

How about Kristen Bell..?

This is a role Helena was born to play.

This "overkill" guy is suck a douche

*such

Helena or Fairuza!!
Or Christina.

Helena Bonham Carter would do an awesome job as Harley Quinn, however I kind of vision Harley Quinn as being younger and I think Emily Browning would do an awesome job! :)

Sienna Miller, or Joanna García

Um... I think all of them could pull it off since they are all great actresses (except the turd thing) but if you think about her personality and looks... I'd cut Helena since she's a) too old in my opinion and b) just not really fitting my discription. (Though I adore her) but really I think Rachel Mcadams would be good or Reese or Brittnay. I think those are my top 3. :)

Oh my God. I didn't know Brittnay Murphy was DEAD! 0_0 :( x10000
I guess she'll never play Harley D: Too bad she'd be really good...