Ned Beatty plays Lotso Huggin' Bear. Beatty has played in such films as the Superman movies and The Big Easy. He has starred in MANY TV movies.
Ned Beatty uses an old New Orleans drawl for Lotso's character, to convey a sense of laid back ease, to further fool you with Lotso's personality. He did a great job, don't you think?
Sources: IMDb and the Toy Story 3 DVD special features