Do you think Lisa will be killed off?

I think so. A demon will posess her and Dean will have to kill her. mwhahaha.

I don't think they will do that, she has Ben and they'd have to kill him too. I don't think Dean would handle THAT very well. They will probably just have her and Ben go on with there lives, after all, she was dating someone new^-^

It depends.
If the apocalypse happens, everyone is killed of(or the series has to continue in hell...). x3

i'd like that so much..but i just think that demons'll used lisa and ben to trap dean..after that she'll never want to see him again and i'll be very but very very happy because i dislike her and his boy..bye bye lisa/ben..and never get back...
but they'll die, i'll be more than happy but i think to our poor dean, he's gonna hate himself for that...so just a goodbye forever...

maybe but i highly doubt that
1. because of Ben and no one wants to see him become an orphan
2. Dean would be crushed! and we don't want s depressed Dean now do we?? I did not think so :)

hell yes and about damn time too sorry but no woman lives on that show I kind of wish they have some girl live to see another day on supernatural but I do not think so.

Yes I think it's very likely
Because they have said that the next last episode will be Dean centric and he will have to face something horrible and I know that Lisa&Ben will appear again around the finale so I think that something horrible will happen to them. And I'm acutally glad if they'll die because then Dean can go back being old Dean than worry all the time about Lisa&Ben